Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-propargyl-O-PEG4-OH Synonyms Thalidomide-4'-propargyl-O-PEG4-OH

Product Name Thalidomide-propargyl-O-PEG4-OH Synonyms Thalidomide-4'-propargyl-O-PEG4-OH CAS Number n/a Related CAS Molecular Formula C24H28N2O9 Molecular Weight 488

347 Purity (HPLC) >= 95% Solubility DMSO

Cy3-CA CAS Number Related CAS Molecular Formula C40H57ClN3O3 Molecular Weight 663

1 SMILES ClC1=CC(Cl)=C(C=C1)C(=O)NS(=O)(=O)C1=CC=C(Br)S1 Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:5mg Product Name Thalidomide-propargyl-O-PEG4-OH Synonyms Thalidomide-4'-propargyl-O-PEG4-OHSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,